Nanomechanical properties of MscL α helices: A steered molecular dynamics study
نویسندگان
چکیده
منابع مشابه
Gating of MscL studied by steered molecular dynamics.
Steered molecular dynamics simulations of the mechanosensitive channel of large conductance, MscL, were used to investigate how forces arising from membrane tension induce gating of the channel. A homology model of the closed form of MscL from Escherichia coli was subjected to external forces of 35-70 pN applied to residues near the membrane-water interface. The magnitude and location of these ...
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ژورنال
عنوان ژورنال: Channels
سال: 2017
ISSN: 1933-6950,1933-6969
DOI: 10.1080/19336950.2016.1249077